


105 N Main Street, Syracuse, NY, 13212
Bedroom
0 Rooms
Bathroom
0 Bath
Square Foot
2244 Ft
Lot Size
0.23 Acres
Well-maintained, single-story commercial building at 105 N Main Street in North Syracuse, NY. This 2,244 square foot medical office has been in continuous professional use for over 60 years and currently houses an established optometry practice operating at this location for 29 years. The building sits on a 0.23-acre lot with 15 dedicated parking spaces and offers high visibility on North Main Street. The property received a new roof in 2024, significantly reducing near-term capital expenditure risk for the buyer. The interior features a professionally designed layout with reception and optical retail areas, multiple fully equipped exam rooms, private offices, and a laboratory space. The floor plan is well-suited for optometry, ophthalmology, dental, dermatology, chiropractic, physical therapy, counseling, or general professional office use. Key property details: 2,244 SF on a single level. Built in 1950, well-maintained with a modern interior buildout. New roof installed in 2024. 15 on-site parking spaces (approximately 7 per 1,000 SF). Zoned for medical and professional office use. Single-tenant, owner-occupied. This property is located in the heart of North Syracuse, within the rapidly growing Central New York economic corridor. The area is positioned to benefit significantly from the Micron Technology semiconductor fabrication facility currently under construction in nearby Clay, NY, which is expected to bring substantial job growth and commercial demand to the surrounding communities. The building is available on its own at $400,000 or as part of a package with the established optometry practice (offered separately at $550,000). Seller financing may be available for qualified buyers.
Contact Agent
Syracuse Expert Agent
Additional Listing Details:
28 days on HouseJet
Last Refresh: 06/17/2026 01:00:04 PM UTC
MLS #: S1683136
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Listing Agent
Jason Klink
License # 10401298650
Home With Us Realty Group, LLC
Phone: 315-569-8931